News

New publication: The Found Down Patient

Congratulations to partner Dr. Matthew Carrick, and collaborators from the The Western Trauma Association Multicenter Trials Committee, for their most recent publication, entitled “The found down patient: A Western Trauma Association multicenter study.”

The article will be published in the upcoming edition of the Journal of Trauma and Acute Care Surgery, and is currently available ahead of publication on Pubmed.

New publication: Management of patients with extra-axial mass lesion and GCS 3

Prognosis in patients with traumatic brain injury (TBI) and Glasgow Coma Scale (GCS) score of 3 is poor, raising concern regarding the utility of aggressive operative neurosurgical management.

We are excited to publish a study describing outcomes in a propensity matched population with TBI and GCS3 treated with operative neurosurgical procedures of craniotomy or craniectomy (CRANI) in Injury this month! Of 541 patients treated over five years and across three trauma centers, we found survival was achieved in 65% of patients that underwent surgical intervention for subdural and epidural haematoma, despite a presenting GCS of 3, demonstrating prompt operative neurosurgical management of mass lesion is warranted for selected patients with a GCS of 3, contributing to a significant 4-fold survival benefit. In the absence of mass lesion the effect of immediate neurosurgery on outcomes is inconclusive.

Read the full article here.

Abstract to be presented at the Society for Redox Biology and Medicine!

We are excited to announce we will be presenting our findings on the following study at the Society for Redox Biology and Medicine: “A new method to assess oxidative stress changes induced by one hemodialysis session.” Our poster presentation will take place on Thursday, November 19, between 4:15 and 6:45 at the Westin Boston Waterfront Hotel in Boston, Massachusetts.

 

 

 

New publication: Lights and siren use in EMS

We are excited our multi-center study examining the frequency and precision of lights and siren use in metro Denver and Colorado Springs is now available. Published in Prehospital Emergency Care, the study found that of the nearly 20% of patients transported with L&S, less than a quarter warranted the high-risk response, as measured by the receipt of a time critical hospital intervention within 15 minutes of hospital arrival. The study suggests an opportunity for further reduction of L&S transports in trauma patients. Read more about the study here.

Trauma Research at the AAST

Thanks to all that stopped by our posters and podium presentations at the 74th Annual Meeting of the AAST and Clinical Congress of Acute Care Surgery last week – it was a great conference!

FullSizeRender

New publication: Oxidative Stress in Septic and Obese Patients

We are proud to have published an additional study examining oxidative stress measured via oxidation reduction potential (ORP), specifically static (sORP) and capacity (cORP) oxidation-reduction potential markers as well as conventional oxidative stress biomarkers of total antioxidant capacity (TAC), thiobarbituric acid-reactive substances (TBARS) and protein carbonyls (CARB), in plasma of patients with sepsis. Further, the effect of obesity-induced oxidative stress on patients with sepsis was also studied. It was found the sORP marker was significantly higher in the sepsis group, while cORP was significantly lower compared to the control group, indicating oxidative stress.Furthermore, in patients with sepsis, TAC was significantly lower compared to control group. However, obesity had no effect on sORP, cORP and TAC in patients with sepsis, although it increased levels of CARB and TBARS. The present results suggest, for the first time, that ORP markers could be used for assessing oxidative stress in patients with sepsis. We recommend reviewing the full article in In Vivo!

 

 

 

Trauma Research presentation schedule: 2015 AAST

Trauma Research is proud to be presenting the following presentations next week at the 74th Annual Meeting of AAST and Clinical Congress of Acute Care Surgery located at the Wynn, Las Vegas, NV:

Wednesday, September 9; 1:20-1:40 in the Latour Ballroom

INTRAOPERATIVE HYPOTENSIVE RESUSCITATION FOR PATIENTS UNDERGOING LAPAROTOMY OR THORACOTOMY FOR TRAUMA: EARLY TERMINATION OF A RANDOMIZED PROSPECTIVE CLINICAL TRIAL, Presented by Dr. Matthew Carrick

Wednesday, September 9; 5:30-7:30 in the LaFite Ballrooms

TYPE 1 DIABETES INCREASES ODDS OF VENOUS THROMBOEMBOLISM FOLLOWING TRAUMATIC INJURY, Presented by Jan Leonard

PROGNOSIS OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY WITH GLASGOW COMA SCALE OF 3 IS PREDICTED BY SIMPLE CRITERIA KNOWN ON ED ARRIVAL, Presented by Kristin Salottolo

THE RISK OF NEUROSURGERY AND MORTALITY IN A POPULATION WITH MILD TRAUMATIC BRAIN INJURY AND INTRACRANIAL HEMORRHAGE: A THREE-YEAR MULTI-CENTER RETROSPECTIVE OBSERVATIONAL STUDY, Presented by Alessandro Orlando

 

Safe boating is no accident, and there’s a study to prove it.

During these dog days of summer, it seems everyone is trying to find just one day to spend on the lake. A recent study in the journal Risk Analysis found increasing the use of life jackets by just 20% would have saved the lives of 1721 American boaters, out of the 3047 boat-involved fatalities within a four year period. Using data from the U.S. Coast guard, the study found the presence of a life jacket increased the odds of surviving a boating accident by 80%. It is hopeful that such a finding can spur evidence-based policy change in the near future. Read the full version here.

Assessing oxidation reduction potential

Congratulations to Leonard Rael and team for recently publishing a manuscript describing the technical components of the electrode that measures oxidation reduction potential. Read more in Electroanalysis.

Intra-Arterial Therapy is Safe and Effective in Patients Aged >80

We are excited to announce a new publication on intra-arterial therapy in patients ≥80 years old, in the most recent issue of Cerebrovascular Diseases.

Recently, clinical trials confirmed the safety and efficacy of performing intra-arterial therapy to manage patients with ischemic stroke. In our recent study, we compared outcomes in patients aged ≥80 to patients in the age range 55-79 years who were treated with intra-arterial therapy after ischemic stroke at a community hospital.

No differences were found in mortality, symptomatic hemorrhage rate, or functional outcomes between the two age groups, suggesting age ≥80 should not be a contraindication to IAT.

Read more in Cerebrovascular Diseases.