New publication: Oxidative Stress in Septic and Obese Patients

We are proud to have published an additional study examining oxidative stress measured via oxidation reduction potential (ORP), specifically static (sORP) and capacity (cORP) oxidation-reduction potential markers as well as conventional oxidative stress biomarkers of total antioxidant capacity (TAC), thiobarbituric acid-reactive substances (TBARS) and protein carbonyls (CARB), in plasma of patients with sepsis. Further, the effect of obesity-induced oxidative stress on patients with sepsis was also studied. It was found the sORP marker was significantly higher in the sepsis group, while cORP was significantly lower compared to the control group, indicating oxidative stress.Furthermore, in patients with sepsis, TAC was significantly lower compared to control group. However, obesity had no effect on sORP, cORP and TAC in patients with sepsis, although it increased levels of CARB and TBARS. The present results suggest, for the first time, that ORP markers could be used for assessing oxidative stress in patients with sepsis. We recommend reviewing the full article in In Vivo!